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%T Int. Conf. on Intelligent Systems for Molecular Biology
%K ISMB, ISCB, ISMB94,ISMB2,1994, ISMB95,ISMB3,1995, ISMB96,ISMB4,1996,
ISMB97,ISMB5,1997, ISMB98,ISMB6,1998, ISMB99,ISMB7,1999, ISMB8,2000,
ISMB9,2001, ISMB10,2002, ISMB11,2003, ISMB12,2004, ISMB13,2005, ISMB14,2006,
ISMB15,2007, ISMB16,2008, ISMB17,2009, ISMB18,2010, ISMB19,2011, ISMB20,2012,
ISBM21,2013, ISMB22,2014, ISMB23,2015, ISMB30,2022
MolBio,conf,CFP,conference,bioinformatics,AI,II,www,HREF,http, zz0122,zz0123
%X [ISMB-30] 10-14 July 2022, Madison Wisc., deadline 13 Jan 2022
...
[ISMB-23] 10-14 July 2015, Dublin (with ECCB), deadline 16 Jan 2015
...
%A W. F. Lunnon
%T Four combinatorial problems
%J ???
%I Atlas Computer Laboratory
%V ??
%M JAN
%D 1971
%P 35-38
%K pentominoe, polyominoe, map fold maps folding, Dedekind's problem,
postage stamp stamps, combinatorics, count, generate, enumerate,
c1971, c197x, c19xx, zz0122
%X "This article is a brief review of four problems we have attacked in the past
few years. They all share the following characteristics: they are intuitively
appealing and easy to pose; but they are (it seems) impossible to solve in
any meaningful sense, and the only effective computational approach to them
is direct enumeration; the functions f(n) involved grow exponentially, and
with them the computing time required; but the computer space required is
very small. ..."
-- paper@[www]['22].
%A H. Bunke
%A Xiaoyi Jiang
%T Graph matching and similarity
%J Intell. Sys. and Interf.
%I Springer
%P 281-304
%D 2000
%K c2000, c200x, c20xx, zz0122, maths, graph, matching, similar, similarity,
inexact, edit distance
%X "Many graphical interfacing problems relay on g.matching. ... we explore &
illustrate how g.matching can be performed using powerful,'intelligent'
algs., to improve std methods."
-- [doi:10.1007/978-1-4615-4401-2_10]['22].
Also see GM@[wilip]['22'.
[Also search for: graph edit distance].
%A M. A. Bender
%A B. C. Kuszmaul
%A W. Kuszmaul
%T Linear probing revisited: Tombstones mark the death of primary clustering
%J arXiv
%M JUK
%D 2021
%O ? FOCS, Feb 2022 ?
%K TR, c2021, c202x, c20xx, zz0122, linear hashing, hash table, data structure,
DS, dataStucture, probing, tombstone, insertion, deletion
%X "... widely believed & taught, however, that linear probing should
never be used at high load factors; this is because primary-clustering
effects cause insertions at load factor 1−1/x to take expected time
Theta(x^2) (rather than the ideal Theta(x)). The dangers of primary
clustering, first discovered by Knuth in 1963, have been taught to
generations of comp.scientists, & have influenced the design of some of many
widely used hash tables. We show that primary clustering is not a foregone
conclusion. We demonstrate that small design decisions in how delns are
implemented have dramatic effects on the asymptotic performance of insertions
so that, even if a hash table operates continuously at a load factor
1−Theta(1/x), the expected amortized cost per operation is ~O(x). ..."
-- 2107.01250@[arXiv]['22].
%A S. Rajapaksa
%A D. Sumanaweera
%A M. Garcia de la Banda
%A P. Stuckey
%A D. Abramson
%A L. Allison
%A A. Lesk
%A A. Konagurthu
%Y On identifying statistical redundancy at the level of amino acid subsequences
%J Int. Conf. on Bioinformatics and Biomedicine (BIBM)
%M DEC
%D 2021
%K conf, c2021, c202x, c20xx, zz0122, MolBio, LAllison, AMLesk, ArunK,
protein, information content, stats, compress, compression, library,
fragments, sequence, subsequence, structure, indels, source code
%X "... presents a framework to characterize & identify local sequences of
proteins that are statistically redundant under the measure of Shannon
information content while accounting for variations in their occurrences over
evolutionary insertions, deletions, & substitutions of amino acids. The
identification of such local seqs. provides insights for downstream studies
on proteins. Here, we have applied our methods to amino acid seq. data sets
derived from a database corr.to 935,552 substructural regions of varying
sizes, covering 113,724 proteins from the protein data bank. The results
identify, among others, a surjective mapping between 110,598 local seqs.
(with an avg. length of 82 AAs/seq.) & 1,493 topological shapes. ..."
-- [doi:10.1109/BIBM52615.2021.9669282]['22],
[more].
Also see supplementary@[lcb]['22].
[Also search for: MolBio protein compression].
%A D. Adjeroh
%A Fei Nan
%T On compressibility of protein sequences
%J Proc. the Data Comp. Conf.
%M MAR
%D 2006
%K conf, DCC, MolBio, c2006, c200x, c20xx, zz0122, protein, compress, BW,
compression, ProtComp, Hategan, Tabus
%X "... Based on an observed genome-scale long-range correlation in concatenated
protein seqs. from different organisms, we propose a method to exploit this
unusual redundancy in compressing the p.seqs.. The result is a sig. reduction
in the # of bits required for representing the seqs.. We report results in
bits per symbol (bps) of 2.27, 2.55, 3.11 & 3.44 for p.seqs. from
M.jannaschii, H.influenzae, S.cerevisiae, & H.sapiens ..."
-- [doi:10.1109/DCC.2006.56]['22].
(*NB. Some of these numbers are rather "surprising"...
"Note that an incorrect protein corpus that was more compressible
somehow got into circulation at some point, resulting in sig. lower
compression figures being reported by ProtComp (Hategan & Tabus, 2004)
& BW (Adjeroh & Nan, 2006). The compression results of ProtComp on the
correct protein corpus were obtained from the author's website. The
authors of BW have 'moved to new projects' (Nan, 2006) so proper
compression results for BW are not available." -- MDC *)
[Also search for: MolBio protein compression].
%A C. D. Wallis
%A et al
%T Association of surgeon-patient sex concordance with postoperative outcomes
%J JAMA Surgery
%M DEC
%D 2021
%K jrnl, c2022, c202x, c20xx, zz0122, human, health, risks, hospital, surgery,
patient, surgeon, male, female, doctor, sex, gender, operation, outcome
%X "... Sex discordance between surgeon & patient was assoc. with a sig.
increased likelihood of composite adverse postoperative outcomes (adjusted
odds ratio [aOR], 1.07; 95% CI, 1.04-1.09), as well as death (aOR, 1.07;
95% CI, 1.02-1.13), & complications (aOR, 1.09; 95% CI, 1.07-1.11) but not
readmission (aOR, 1.02; 95% CI, 0.98-1.07). While assocs. were consistent
across most subgroups, patient sex sig. modified this assoc., with worse
outcomes for female patients treated by male surgeons (compared with female
patients treated by female surgeons: aOR, 1.15; 95% CI, 1.10-1.20) but not
male patients treated by female surgeons ..."
-- [doi:10.1001/jamasurg.2021.6339]['22].
(Also see The G [www][4/1/2022].)
%A L. J. Underland
%T The impact of weight change and measures of physical functioning on mortality
%J J. Amer. Geriatrics Soc.
%V ?
%P ?-?
%M JAN
%D 2022
%K jrnl, c2022, c202x, c20xx, zz0122, stats, human, health, medicine, ageing,
longevity, risk, risks, mortality, lifespan, gender, women, weight,
grip strength
%X "Lower grip strength & measures of physical functioning are assoc. with
all-cause mortality. Relationships among long-term weight loss, physical
functioning, & mortality in older women are understudied. ... Weight loss of
5% or more percent body weight was assoc. with a hazard ratio of 1.66
(1.37-2.01) for all-cause mortality. Weight gain was not related to mortality
or cardiovascular outcomes. Those in the highest grip strength quartile had a
hazard ratio of 0.51 (0.39-0.66) for all-cause mortality. ..."
-- [doi:10.1111/jgs.17626]['22] (online Jan 2022).
[Also search for: lifespan ageing].
%A K. Bjornevik
%A et al
%T Longitudinal analysis reveals high prevalence of Epstein-Barr virus
associated with multiple sclerosis
%J Science
%V ?
%M JAN
%D 2022
%K jrnl, c2022, c202x, c20xx, zz0122, human health, multiple sclerosis, MS,
medicine, cause, stats, B cell, Bcell, LMP1, LMP2A, Epstein Barr virus, EBV,
glandular fever, autoimmune, disease, risk, risks
%X "... tested the hypothesis that MS is caused by ... (EBV) in a cohort
comprising more than 10 million young adults on active duty in the US mil.,
955 of whom were diagnosed with MS during their period of service. Risk of
MS increased 32-fold after infection with EBV but was not increased after
infection with other v., inc. the similarly transmitted cytomegalovirus.
Serum levels of neurofilament light chain, a biomarker of neuroaxonal
degeneration, increased only after EBV seroconversion. These findings cannot
be explained by any known risk factor for MS & suggest EBV as the leading
cause of MS."
-- [doi:10.1126/science.abj8222]['22] (online Jan 2022).
(Also see persp@[doi:10.1126/science.abm7930][13/1/2022].)
%A G. G. Rosenthal
%A M. J. Ryan
%T Sexual selection and the ascent of women: Mate choice research since Darwin
%V 375
%N 6578
%M JAN
%D 2022
%K jrnl, c2022, c202x, c20xx, zz0122, mate selection, mating, sex, sexual,
human behaviour, men, women, attraction, biology, biol
%X "Darwin's theory of sexual selection fundamentally changed how we think about
sex & evolution. ... Contemporaries dismissed D's conjecture of a 'taste for
the beautiful' as favoring particular mates over others, but there is now
overwhelming evidence for a primary role of both male & female mate choice in
sexual seln. D's misogyny precluded much analysis of the 'taste'; an
increasing focus on mate choice mechanisms before, during, & after mating
reveals that these often evolve in response to seln pressures that have
little to do with sexual seln on chosen traits. ..."
-- [doi:10.1126/science.abi6308]['22],
auth1[www]['22],
auth2[www]['22].
[Also search for: mate selection].
%A C. Anderseon
%T The end of theory: The data deluge makes the scientific method obsolete
%J Wired
%M JUN
%D 2008
%K views, opinion, c2008, c200x, c20xx, zz0122, big data, bigData, theory,
hypothesis, explanation, inference, science, scientific method, correlation
%X "'All models are wrong, but some are useful.' So proclaimed statistician
George Box 30 years ago, & he was right. But what choice did we have? ..."
-- [www]['22].
%A J. C. Peterson
%A et al
%T Using large-scale experiments and machine learning to discover theories of
human decision-making
%J Science
%V 372
%N 6547
%P 1209-1214
%M JUN
%D 2021
%K jrnl, c2021, c202x, c20xx, zz0122, human thought, decision making, choice,
behaviour
%X "... using large datasets to power machine-learning algs. that are
constrained to produce interpretable psychological theories. Conducting the
largest experiment on risky choice to date & analyzing the results using
gradient-based optimization of differentiable decision theories implemented
through [ANNs], we were able to recapitulate historical discoveries,
establish that there is room to improve on existing theories, & discover a
new, more accurate model of human decision-making in a form that preserves
the insights from centuries of research."
-- [doi:10.1126/science.abe2629]['22].
[Also search for: human decision making].
%A L. Henriet
%A et al ...
%A C. Jurczak
%T Quantum computing with neutral atoms
%J arXiv
%M JUN
%D 2020
%O Quantum J., vol.4, p.327, Sep. 2020
%K TR, c2020, c202x, c20xx, zz0122, quantum, computing, qubit, neutral atom
%X "... review the main characteristics of these devices from atoms/qubits to
application interfaces, & propose a class'n of a wide variety of tasks that
can already be addressed in a computationally efficient manner in the Noisy
Intermediate Scale Quantum era we are in. We illustrate how applic'ns ranging
from optimization challenges to simulation of q.systems can be explored
either at the digital level (programming gate-based circuits) or at the
analog level (programming Hamiltonian seqs.). We give evidence of the
intrinsic scalability of neutral atom q.processors in the 100-1,000 qubits
range & intro. prospects for universal fault tolerant q.computing &
applications beyond q.computing."
-- [arXiv]['22] and in
QJ[doi:10.22331/q-2020-09-21-327]['22].
[Also search for: quantum computing].
%A E. Adlam
%T Determinism beyond time evolution
%J arXiv
%M OCT
%D 2021
%K TR, physics, c2021, c202x, c20xx, zz0122, time, arrow, determinism, chance
%X "... we use a constraint-based framework to set out a generalization of
determinism which does not presuppose temporal directedness, distinguishing
between strong, weak & delocalised global determinism. We discuss some
interesting consequences of these generalized notions of determinism, & we
show that this approach sheds new light on the long-standing debate
surrounding the nature of objective chance."
-- 2110.07656@[arXiv]['22],
auth@[sch'lar]['22].
[Also search for: time arrow].
%A H. Bannai
%A Tomohiro I
%A T. Kociumaka
%A D. Koppl
%A S. J. Puglisi
%T Computing longest (common) Lyndon subsequences
%J arXiv
%M JAN
%D 2022
%K TR, c2022, c202x, c20xx, zz0122, Lyndon, word, words, LyndonWord, factors,
subsequence, string, strings, longest common Lyndon subsequence, LCLS,
algorithm
%X "Given a string T with length n whose characters are drawn from an ordered
alphabet of size s, its longest Lyndon subsequence is a longest subseq. of
T that is a Lyndon word. We propose algs. for finding such a subseq. in
O(n^3) time with O(n) space, or online in O(n^3s) space & time. Our 1st
result can be extended to find the longest common L. subseq. of two strings
of length n in O(n^4s) time using O(n^3) space.
-- 2201.06773@[arXiv]['22].
[Also search for: LyndonWord].
%T The online information environment: Understanding how the internet shapes
people's engagement with scientific information
%I The Royal Soc.
%M JAN
%D 2022
%K report , news, views, c2022, c202x, c20xx, zz0122, internet, www, twitter,
meta, facebook, reddit, social media, fake news, fakeNews, misinformation,
malinformation, deepfake, removal, dePlatform, deplatforming, trumpery,
altRight, 4chan, QQ, Qanon, antivax
%X uk us isbn13:9781782525677.
"How are digital technologies changing the way people interact with
information? What technologies are there that can fabricate & detect
misinformation? And what role does technology have to play in creating a
better information environment? ..."
-- [www]['22].
(Also see [bbc][19/1/2022].)